Renal Tubulointerstitial Lesions in Mercuric Chloride-Treated F344 Rats.
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چکیده
منابع مشابه
Melatonin attenuates acute renal failure and oxidative stress induced by mercuric chloride in rats.
We evaluated the effect of melatonin (Mel), a potent scavenger of reactive oxygen species, in the course of HgCl(2)-induced acute renal failure. Rats received by gastric gavage 1 mg/kg of Mel (n = 21) or vehicle (n = 21), 30 min before the subcutaneous injection of HgCl(2) (2.5 mg/kg). Rats were killed at 24, 48, and 72 h, and plasma creatinine (S(cr)), renal histology, proliferative activity, ...
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ژورنال
عنوان ژورنال: Journal of Toxicologic Pathology
سال: 2000
ISSN: 0914-9198,1881-915X
DOI: 10.1293/tox.13.213